Benzoyl chloride → HCID 178426255, compound

Participants

Reaction Steps

To a stirred solution of 4-amino-5-(4'-methylphenyl)pyrazolo[3,4-d]pyrimidine (0.40 g, 1.77 mmol) in pyridine (9 mL) was added benzoyl chloride (0.25 g, 1.77 mmol) dropwise. After 45 minutes, the pyridine was removed in vacuo and the resulting solids were washed with water and EtOH to afford 0.28 g of the title compound; m.p. 297°-300° C. Anal. calcd. for C19H15N5.0.75 H2O: C, 66.55; H, 4.85; N, 20.42. Found: C, 6.43; H, 4.69; N, 19.77.

Provenance & Evidence