5-[4-ethyl-5-[4-(1,3-thiazol-5-yl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]-pyridinesulfonamide → 5-{4-Fluoro-5-[4-(1,3-thiazol-5-yl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl}-2-pyridinesulfonamide
Reaction equation
[Br:33][c:34]1[cH:35][cH:36][c:37]([C:38]2([CH2:39][CH3:40])[N:41]([c:42]3[cH:43][cH:44][c:45]([S:46]([NH2:47])(=[O:48])=[O:49])[n:50][cH:51]3)[NH:52][C:53]([C:54]([F:55])([F:56])[F:57])=[CH:58]2)[cH:59][cH:60]1.[CH2:1]([CH3:2])[c:3]1[c:4]([C:29]([F:30])([F:31])[F:32])[n:5][n:6](-[c:19]2[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[NH2:28])[n:23][cH:24]2)[c:7]1-[c:8]1[cH:9][cH:10][c:11](-[c:14]2[cH:15][n:16][cH:17][s:18]2)[cH:12][cH:13]1>>[c:3]1([F:56])[c:4]([C:29]([F:30])([F:31])[F:32])[n:5][n:6](-[c:19]2[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[NH2:28])[n:23][cH:24]2)[c:7]1-[c:8]1[cH:9][cH:10][c:11](-[c:14]2[cH:15][n:16][cH:17][s:18]2)[cH:12][cH:13]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ec45e0f00fe649c98ac9c3ca0592a00e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…