Ethyl bromoacetate → {4-[2-(Benzylcarbamoyl-methyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl]-2-methoxy-phenoxy}-acetic acid ethyl ester

HRID 2336720Notes

Reaction equation

HRID 2336720 reaction equation
[Br:36][CH2:37][C:38](=[O:39])[O:40][CH2:41][CH3:42].[OH:1][c:2]1[c:3]([O:34][CH3:35])[cH:4][c:5]([CH2:6][CH:7]2[N:8]([CH2:21][C:22](=[O:23])[NH:24][CH2:25][c:26]3[cH:27][cH:28][cH:29][cH:30][cH:31]3)[CH2:9][CH2:10][c:11]3[cH:12][c:13]([O:19][CH3:20])[c:14]([O:17][CH3:18])[cH:15][c:16]32)[cH:32][cH:33]1>>[O:1]([c:2]1[c:3]([O:34][CH3:35])[cH:4][c:5]([CH2:6][CH:7]2[N:8]([CH2:21][C:22](=[O:23])[NH:24][CH2:25][c:26]3[cH:27][cH:28][cH:29][cH:30][cH:31]3)[CH2:9][CH2:10][c:11]3[cH:12][c:13]([O:19][CH3:20])[c:14]([O:17][CH3:18])[cH:15][c:16]32)[cH:32][cH:33]1)[CH2:37][C:38](=[O:39])[O:40][CH2:41][CH3:42]

Participants

3

Reactant 2

HCID 7748Ethyl bromoacetateHCID 227426752-[1-(4-hydroxy-3-methoxy-benzyl)6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-benzyl-acetamide

Product 1

HCID 69759891{4-[2-(Benzylcarbamoyl-methyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl]-2-methoxy-phenoxy}-acetic acid ethyl ester

Sources & evidence

ORD record
ord-e0a3ace560b34506b2bb747cd6c27adf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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