tert-Butylsulfonamide → N-(1-Ethyl-1H-indol-6-yl)-4-[4-(2-methyl-propane-2-sulfonylaminocarbonyl)-piperidin-1-yl]-benzamide

HRID 2336963Notes

Reaction equation

HRID 2336963 reaction equation
[C:30]([CH3:31])([CH3:32])([CH3:33])[S:34](=[O:35])(=[O:36])[NH2:37].[CH2:1]([CH3:2])[n:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][c:9]([NH:12][C:13](=[O:14])[c:15]3[cH:16][cH:17][c:18]([N:21]4[CH2:22][CH2:23][CH:24]([C:27](=[O:28])[OH:29])[CH2:25][CH2:26]4)[cH:19][cH:20]3)[cH:10][c:11]12.[I:38][c:39]1[cH:40][cH:41][c:42]([NH:43][C:44]([c:45]2[cH:46][cH:47][c:48]([N:49]3[CH2:50][CH2:51][CH:52]([C:53]([NH:54][S:55]([C:56]([CH3:57])([CH3:58])[CH3:59])(=[O:60])=[O:61])=[O:62])[CH2:63][CH2:64]3)[n:65][cH:66]2)=[O:67])[cH:68][c:69]1[CH3:70]>>[CH2:1]([CH3:2])[n:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][c:9]([NH:12][C:13](=[O:14])[c:15]3[cH:16][cH:17][c:18]([N:21]4[CH2:22][CH2:23][CH:24]([C:27](=[O:28])[NH:37][S:34]([C:30]([CH3:31])([CH3:32])[CH3:33])(=[O:35])=[O:36])[CH2:25][CH2:26]4)[cH:19][cH:20]3)[cH:10][c:11]12

Participants

4

Reactant 3

HCID 2757335tert-ButylsulfonamideHCID 593179844-(2-methyl-propane-2-sulfonylaminocarbonyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-5'-carboxylic acid (4-iodo-3-methyl-phenyl)-amideHCID 593180471-[4-(1-Ethyl-1H-indol-6-ylcarbamoyl)-phenyl]-piperidine-4-carboxylic acid

Product 1

HCID 59318059N-(1-Ethyl-1H-indol-6-yl)-4-[4-(2-methyl-propane-2-sulfonylaminocarbonyl)-piperidin-1-yl]-benzamide

Sources & evidence

ORD record
ord-6c8d8095e5564e279bfdd61d8efec783
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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