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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 233739Generated: October 29, 2026

Tranylcypromine, cis- → (+)-N-(cis-2-phenylcyclopropyl)-N'-(5-chloropyrid-2-yl)thiourea

https://huagongshe.com/reaction/233739

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTranylcypromine, cis-HCID 6971118—
ReactantN-(5-Chloropyridin-2-yl)-1H-imidazole-1-carbothioamideHCID 10823879—
Product(+)-N-(cis-2-phenylcyclopropyl)-N'-(5-chloropyrid-2-yl)thioureaHCID 22868897—

Reaction Steps

(-)-N-cis-2-phenylcyclopropylamine (0.23 g, 1.7 mmol) from Example 423 was condensed with 1-(5-chloropyrid-2-yl-thiocarbamoyl)-imidazole (0.4 g, 1.7 mmol) according to the procedure of Example 372 to yield the titled product as crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05593993
Source datasetuspto-grants-1997_01
ORD IDord-2930949b6fcd4e8296d9d66cd582537e
Source noteuspto-grants-1997_01