3-Chlorobenzo(b)thiophene-2-carbonyl chloride → tert-Butyl (4-{(3-chloro-benzo[b]thiophene-2-carbonyl)-[4-methoxy-4'-(2,2,2-trifluoro-acetyl)-biphenyl-3-ylmethyl]-amino}-cyclohexyl)-methyl-carbamate
Reaction equation
[CH3:1][O:2][c:3]1[c:4]([CH2:21][NH:22][CH:23]2[CH2:24][CH2:25][CH:26]([N:29]([C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[CH3:37])[CH2:27][CH2:28]2)[cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([C:15]([C:16]([F:17])([F:18])[F:19])=[O:20])[cH:13][cH:14]2)[cH:7][cH:8]1.[Cl:38][c:39]1[c:40]2[c:41]([s:42][c:43]1[C:44](=[O:45])[Cl:46])[cH:47][cH:48][cH:49][cH:50]2>>[CH3:1][O:2][c:3]1[c:4]([CH2:21][N:22]([CH:23]2[CH2:24][CH2:25][CH:26]([N:29]([C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[CH3:37])[CH2:27][CH2:28]2)[C:44]([c:43]2[c:39]([Cl:38])[c:40]3[c:41]([s:42]2)[cH:47][cH:48][cH:49][cH:50]3)=[O:45])[cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([C:15]([C:16]([F:17])([F:18])[F:19])=[O:20])[cH:13][cH:14]2)[cH:7][cH:8]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-0ef543e3f46c42b78f50899c811e294c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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