Sodium ion → Tert-butyl 4-cyclobutylpiperazine-1-carboxylate

HRID 2337475Notes

Reaction equation

HRID 2337475 reaction equation
[C:14]1(=[O:18])[CH2:15][CH2:16][CH2:17]1.[C:19]([O:20][BH-:21]([O:22][C:23](=[O:24])[CH3:25])[O:26][C:27](=[O:28])[CH3:29])(=[O:30])[CH3:31].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[Cl:33][CH2:34][Cl:35].[Na+:32]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH:14]2[CH2:15][CH2:16][CH2:17]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6344DichloromethaneHCID 14496CyclobutanoneHCID 143452tert-Butyl piperazine-1-carboxylateHCID 2724942Triacetoxyborohydride

Product 1

HCID 57423951Tert-butyl 4-cyclobutylpiperazine-1-carboxylate

Sources & evidence

ORD record
ord-2389a5d078374c7aaaec6696c88ac07e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…