4-Chloroaniline → HCID 23358147, compound

HRID 233813Notes

Reaction equation

C(O[C:4](=[O:19])[NH:5][S:6]([C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[N:14]([CH3:18])[CH2:13][CH2:12]2)(=[O:8])=[O:7])C.[Cl:20][C:21]1[CH:27]=[CH:26][C:24]([NH2:25])=[CH:23][CH:22]=1>>[Cl:20][C:21]1[CH:27]=[CH:26][C:24]([NH:25][C:4]([NH:5][S:6]([C:9]2[CH:10]=[C:11]3[C:15](=[CH:16][CH:17]=2)[N:14]([CH3:18])[CH2:13][CH2:12]3)(=[O:7])=[O:8])=[O:19])=[CH:23][CH:22]=1

Participants

Reactant 2

HCID 78124-Chloroaniline

HCID 53647679HCID 53647679, compound

Product 1

HCID 23358147HCID 23358147, compoundYield 60%

Procedure

Following the procedure of Example 3B, the title product was prepared in 60% yield from [(2,3-dihydro-1-methyl-1H-indol-5-yl)sulfonyl]carbamic acid ethyl ester and 4-chloroaniline, m.p. 145°-147° C.

Sources & evidence

ORD record: ord-916b950a5662477c88f8d6a488953408
Source dataset: uspto-grants-1997_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05594028

Reaction notes

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