Sodium Hydroxide → HCID 77324662, compound

HRID 233816Notes

Reaction equation

HRID 233816 reaction equation
C([O:3][C:4]([C:6]1([C:31]([O:33]CC)=[O:32])[O:10][C:9]2[C:11]3[CH2:12][CH:13]([N:18]4[CH2:22][CH:21]([C:23]5[CH:28]=[CH:27][CH:26]=[C:25]([Cl:29])[CH:24]=5)[O:20]C4=O)[CH2:14][C:15]=3[CH:16]=[CH:17][C:8]=2[O:7]1)=[O:5])C.[OH-].[Na+:37]>>[Na+:37].[Na+:37].[Cl:29][C:25]1[CH:24]=[C:23]([CH:21]([OH:20])[CH2:22][NH:18][CH:13]2[CH2:12][C:11]3[C:9]4[O:10][C:6]([C:4]([O-:5])=[O:3])([C:31]([O-:33])=[O:32])[O:7][C:8]=4[CH:17]=[CH:16][C:15]=3[CH2:14]2)[CH:28]=[CH:27][CH:26]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 54449292HCID 54449292, compound

Product 1

HCID 77324662HCID 77324662, compound

Procedure

The title compound is prepared by the procedure of Example 3 using 1.96 g of product from Example 2 and 27 ml of 2.5N sodium hydroxide. The residue is purified by chromatography as above to give 0.89 g of the desired component as an off white solid, Rf=0.61.

Workup

  1. customThe residue is purified by chromatography as above
  2. customto give 0.89 g of the desired component as an off white solid, Rf=0.61

Sources & evidence

ORD record
ord-b9c7298d939247819c0dfe0b3a8840bc
Source dataset
uspto-grants-1997_01
Patent number
US05594027

Reaction notes

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