3-(3,4,5-Trimethoxyphenyl)benzyl chloride → 1-(tert-butoxycarbonyl)-4-[N-(3,4-difluorophenyl)-N-[3-(3,4,5-trimethoxyphenyl)benzyl]amino]piperidine
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][c:15]2[cH:16][c:17]([F:22])[c:18]([F:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH3:23][O:24][c:25]1[cH:26][c:27](-[c:35]2[cH:36][c:37]([CH2:38][Cl:39])[cH:40][cH:41][cH:42]2)[cH:28][c:29]([O:33][CH3:34])[c:30]1[O:31][CH3:32]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([c:15]2[cH:16][c:17]([F:22])[c:18]([F:21])[cH:19][cH:20]2)[CH2:38][c:37]2[cH:36][c:35](-[c:27]3[cH:26][c:25]([O:24][CH3:23])[c:30]([O:31][CH3:32])[c:29]([O:33][CH3:34])[cH:28]3)[cH:42][cH:41][cH:40]2)[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-f7db6583c3004ee3bf1b3fdb471c72f7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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