Dichloromethane → 1-Benzyl 4-tert-butyl piperidine-1,4-dicarboxylate

HRID 2339032Notes

Reaction equation

HRID 2339032 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([C:17](=[O:18])[OH:19])[CH2:15][CH2:16]1.[CH:20]([NH:21][C:22](=[N:23][CH:24]([CH3:25])[CH3:26])[O-:27])([CH3:28])[CH3:29].[CH:30]([NH:31][C:32](=[N:33][CH:34]([CH3:35])[CH3:40])[O:41][C:36]([CH3:37])([CH3:38])[CH3:39])([CH3:42])[CH3:43].[Cl:44][CH2:45][Cl:46]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][CH2:13][CH:14]([C:17](=[O:18])[O:19][C:36]([CH3:37])([CH3:38])[CH3:39])[CH2:15][CH2:16]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7364891-Carbobenzoxy-4-piperidinecarboxylic AcidHCID 110417822-tert-Butyl-1,3-diisopropylisoureaHCID 20470589N,N'-diisopropylimidocarbamate

Product 1

HCID 15126991-Benzyl 4-tert-butyl piperidine-1,4-dicarboxylate

Sources & evidence

ORD record
ord-e25d6fd33be24588b288af1750f7403e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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