Acetonitrile → {8-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethylsulfanyl]-chroman-5-yloxy}-acetic acid methyl ester
Reaction equation
[C:36](=[O:37])([O-:38])[O-:39].[CH3:1][O:2][C:3]([CH2:4][O:5][c:6]1[c:7]2[c:12]([c:13]([SH:16])[cH:14][cH:15]1)[O:11][CH2:10][CH2:9][CH2:8]2)=[O:17].[CH3:42][C:43]#[N:44].[Cl:18][CH2:19][c:20]1[c:21]([CH3:35])[n:22][c:23](-[c:25]2[cH:26][cH:27][c:28]([C:31]([F:32])([F:33])[F:34])[cH:29][cH:30]2)[s:24]1.[Cs+:40].[Cs+:41]>>[CH3:1][O:2][C:3]([CH2:4][O:5][c:6]1[c:7]2[c:12]([c:13]([S:16][CH2:19][c:20]3[c:21]([CH3:35])[n:22][c:23](-[c:25]4[cH:26][cH:27][c:28]([C:31]([F:32])([F:33])[F:34])[cH:29][cH:30]4)[s:24]3)[cH:14][cH:15]1)[O:11][CH2:10][CH2:9][CH2:8]2)=[O:17]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c72b77af997d4a4397a302fb688dd43e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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