Ethanol → 6-({[(1-{2-[3-fluoro-6-(methyloxy)-1,5-naphthyridin-4-yl]ethyl}-3-azetidinyl)methyl]amino}methyl)-2H-pyrido[3,2-b][1,4]thiazin-3(4H)-one
Reaction equation
[BH4-:35].[CH3:40][CH2:41][OH:42].[Cl:37][CH2:38][Cl:39].[F:1][c:2]1[cH:3][n:4][c:5]2[cH:6][cH:7][c:8]([O:20][CH3:21])[n:9][c:10]2[c:11]1[CH2:12][CH2:13][N:14]1[CH2:15][CH:16]([CH2:18][NH2:19])[CH2:17]1.[Na+:36].[O:22]=[C:23]1[CH2:24][S:25][c:26]2[c:27]([n:29][c:30]([CH:33]=[O:34])[cH:31][cH:32]2)[NH:28]1>>[F:1][c:2]1[cH:3][n:4][c:5]2[cH:6][cH:7][c:8]([O:20][CH3:21])[n:9][c:10]2[c:11]1[CH2:12][CH2:13][N:14]1[CH2:15][CH:16]([CH2:18][NH:19][CH2:33][c:30]2[n:29][c:27]3[c:26]([cH:32][cH:31]2)[S:25][CH2:24][C:23](=[O:22])[NH:28]3)[CH2:17]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d8203598f5244117b1004e8760325cee
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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