2-Chloropyridine-4-boronic acid → [6-Bromo-1-(2-chloro-pyridin-4-yl)-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-morpholin-4-yl-methanone

HRID 2339586Notes

Reaction equation

HRID 2339586 reaction equation
[Br:1][c:2]1[c:3]([O:19][CH:20]2[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]2)[cH:4][c:5]2[cH:6][c:7]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[nH:8][c:9]2[cH:10]1.[Cl:29][c:30]1[n:31][cH:32][cH:33][c:34]([B:36]([OH:37])[OH:38])[cH:35]1>>[Br:1][c:2]1[c:3]([O:19][CH:20]2[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]2)[cH:4][c:5]2[cH:6][c:7]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[n:8](-[c:34]3[cH:33][cH:32][n:31][c:30]([Cl:29])[cH:35]3)[c:9]2[cH:10]1

Participants

3

Reactant 2

HCID 51515952-Chloropyridine-4-boronic acidHCID 67017918[6-Bromo-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-morpholin-4-yl-methanone

Product 1

HCID 16739659[6-Bromo-1-(2-chloro-pyridin-4-yl)-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-morpholin-4-yl-methanone

Sources & evidence

ORD record
ord-5e24327ffe774048a43b1e8f25833df8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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