Dichloromethane → 4-[{3-[1-(4-Chloro-phenyl)-1-methyl-ethyl]-pyridin-2-ylmethyl}-(3,5-dimethyl-pyridin-2-ylmethyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][CH2:15][c:16]2[n:17][cH:18][c:19]([CH3:23])[cH:20][c:21]2[CH3:22])[CH2:12][CH2:13]1.[Cl:24][c:25]1[cH:26][cH:27][c:28]([C:31]([CH3:32])([CH3:33])[c:34]2[c:35]([CH:40]=[O:41])[n:36][cH:37][cH:38][cH:39]2)[cH:29][cH:30]1.[Cl:42][CH2:43][Cl:44]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([CH2:15][c:16]2[n:17][cH:18][c:19]([CH3:23])[cH:20][c:21]2[CH3:22])[CH2:40][c:35]2[c:34]([C:31]([c:28]3[cH:27][cH:26][c:25]([Cl:24])[cH:30][cH:29]3)([CH3:32])[CH3:33])[cH:39][cH:38][cH:37][n:36]2)[CH2:12][CH2:13]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-825107ebb45040d893fbbf170894d5eb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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