1-(4-Methylsulphonyloxy-phenoxy)-2,3-epoxypropane → 6-[1-[2-[3-(4-Methylsulphonyloxy-phenoxy)-2-hydroxypropylamino]ethyl]benzimidazol-5-yl]-4,5-dihydro-3(2H)-pyridazinone

HRID 2339845Notes

Reaction equation

HRID 2339845 reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[O:5][c:6]1[cH:7][cH:8][c:9]([O:10][CH2:11][CH:12]2[CH2:13][O:14]2)[cH:15][cH:16]1.[NH2:17][CH2:18][CH2:19][n:20]1[cH:21][n:22][c:23]2[c:24]1[cH:25][cH:26][c:27]([C:29]1=[N:34][NH:33][C:32](=[O:35])[CH2:31][CH2:30]1)[cH:28]2>>[CH3:1][S:2](=[O:3])(=[O:4])[O:5][c:6]1[cH:7][cH:8][c:9]([O:10][CH2:11][CH:12]([CH2:13][NH:17][CH2:18][CH2:19][n:20]2[cH:21][n:22][c:23]3[c:24]2[cH:25][cH:26][c:27]([C:29]2=[N:34][NH:33][C:32](=[O:35])[CH2:31][CH2:30]2)[cH:28]3)[OH:14])[cH:15][cH:16]1

Participants

3

Reactant 2

HCID 115505071-(4-Methylsulphonyloxy-phenoxy)-2,3-epoxypropaneHCID 151078536-[1-(2-aminoethyl)benzimidazol-5-yl]-4,5-dihydro-3(2H)-pyridazinone

Product 1

HCID 151078556-[1-[2-[3-(4-Methylsulphonyloxy-phenoxy)-2-hydroxypropylamino]ethyl]benzimidazol-5-yl]-4,5-dihydro-3(2H)-pyridazinone

Sources & evidence

ORD record
ord-c79698feeadb4d56b33267e3d3507b04
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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