Acetic Acid → 8-(Pyrrolidine-1-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one
Reaction equation
[C:1]([OH:2])(=[O:3])[CH3:4].[F:5][C:6]([O:7][c:8]1[cH:9][cH:10][c:11]([N:14]2[C:15](=[O:24])[C:16]3([CH2:17][CH2:18]2)[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]3)[cH:12][cH:13]1)([F:25])[F:26].[N:27]1([S:32](=[O:33])(=[O:34])[Cl:35])[CH2:28][CH2:29][CH2:30][CH2:31]1>>[F:5][C:6]([O:7][c:8]1[cH:9][cH:10][c:11]([N:14]2[C:15](=[O:24])[C:16]3([CH2:17][CH2:18]2)[CH2:19][CH2:20][N:21]([S:32]([N:27]2[CH2:28][CH2:29][CH2:30][CH2:31]2)(=[O:33])=[O:34])[CH2:22][CH2:23]3)[cH:12][cH:13]1)([F:25])[F:26]Participants
4
Sources & evidence
- ORD record
- ord-82a3a127b288480eaf1160edd1b5505a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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