HRID234028

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID20318569

未命名化合物

结构：CCCc1nc2c(C)cc(-c3nc(C(C)C)c(C)o3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1

HCID67708445

未命名化合物

PRODUCTS

生成物

结构：CCCc1nc2c(C)cc(-c3nc(C(C)C)c(C)n3CC)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1

HCID54472825

未命名化合物

PROCEDURE

实验过程

Prepared analogously to Example 146 from tert.butyl 4'-[[2-n-propyl-4-methyl-6-(4-isopropyl-5-methyl-oxazol-2-yl)-l H-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate and N-ethyl-formamide/ethylamine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ac58506e35574de8a924b851fa31299f
来源数据集: uspto-grants-1997_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05594003
来源说明: uspto-grants-1997_01

反应 SMILES

[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[C:17]([C:22]([O:24]C(C)(C)C)=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:12][CH:11]=2)[C:7]2[CH:29]=[C:30]([C:34]3O[C:36]([CH3:42])=[C:37]([CH:39]([CH3:41])[CH3:40])[N:38]=3)[CH:31]=[C:32]([CH3:33])[C:6]=2[N:5]=1)[CH2:2][CH3:3].[CH2:43]([NH:45]C=O)[CH3:44].C(N)C>>[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:11]=[CH:12][C:13]([C:16]3[C:17]([C:22]([OH:24])=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:14][CH:15]=2)[C:7]2[CH:29]=[C:30]([C:34]3[N:45]([CH2:43][CH3:44])[C:36]([CH3:42])=[C:37]([CH:39]([CH3:41])[CH3:40])[N:38]=3)[CH:31]=[C:32]([CH3:33])[C:6]=2[N:5]=1)[CH2:2][CH3:3]