HRID234030

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCc1nc2c(C)cc(-c3nc(C(C)C)c(C)o3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1

HCID67708445

未命名化合物

HCID86750143

未命名化合物

PRODUCTS

生成物

结构：CCCc1nc2c(C)cc(-c3nc(C(C)C)c(C)n3C3CCCCC3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1

HCID53644445

未命名化合物

PROCEDURE

实验过程

Prepared analogously to Example 146 from tert.butyl 4'-[[2-n-propyl-4-methyl-6-(4-isopropyl-5-methyl-oxazol-2-yl)-1H-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylate and N-cyclohexyl-formamide/cyclohexylamine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8cc6613877b44e0f8985ccafe4bc7e3c
来源数据集: uspto-grants-1997_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05594003
来源说明: uspto-grants-1997_01

反应 SMILES

[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[C:17]([C:22]([O:24]C(C)(C)C)=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:12][CH:11]=2)[C:7]2[CH:29]=[C:30]([C:34]3OC(C)=[C:37]([CH:39]([CH3:41])[CH3:40])[N:38]=3)[CH:31]=[C:32]([CH3:33])[C:6]=2[N:5]=1)[CH2:2][CH3:3].[CH:43]1([NH:49][CH:50]=O)[CH2:48][CH2:47][CH2:46][CH2:45][CH2:44]1.[CH:52]1(N)CCCCC1>>[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:11]=[CH:12][C:13]([C:16]3[C:17]([C:22]([OH:24])=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:14][CH:15]=2)[C:7]2[CH:29]=[C:30]([C:34]3[N:49]([CH:43]4[CH2:44][CH2:45][CH2:46][CH2:47][CH2:48]4)[C:50]([CH3:52])=[C:37]([CH:39]([CH3:40])[CH3:41])[N:38]=3)[CH:31]=[C:32]([CH3:33])[C:6]=2[N:5]=1)[CH2:2][CH3:3]