Dimethyl Sulfoxide → tert-Butyl 3-{5-[2-(2-cyano-4-{[(2,4-dimethoxybenzyl)(1,2,4-thiadiazol-5-yl)amino]sulfonyl}phenoxy)-5-(trifluoromethyl)phenyl]-1H-pyrazol-1-yl}azetidine-1-carboxylate
Reaction equation
[C:28](=[O:29])([O-:30])[O-:31].[C:34](#[N:35])[c:36]1[cH:37][c:38]([S:43](=[O:44])(=[O:45])[N:46]([c:47]2[n:48][cH:49][n:50][s:51]2)[CH2:52][c:53]2[c:54]([O:61][CH3:62])[cH:55][c:56]([O:59][CH3:60])[cH:57][cH:58]2)[cH:39][cH:40][c:41]1[F:42].[CH3:63][S:64]([CH3:65])=[O:66].[K+:32].[K+:33].[OH:1][c:2]1[c:3](-[c:12]2[cH:13][cH:14][n:15][n:16]2[CH:17]2[CH2:18][N:19]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:20]2)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1>>[O:1]([c:2]1[c:3](-[c:12]2[cH:13][cH:14][n:15][n:16]2[CH:17]2[CH2:18][N:19]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:20]2)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1)[c:41]1[c:36]([C:34]#[N:35])[cH:37][c:38]([S:43](=[O:44])(=[O:45])[N:46]([c:47]2[n:48][cH:49][n:50][s:51]2)[CH2:52][c:53]2[c:54]([O:61][CH3:62])[cH:55][c:56]([O:59][CH3:60])[cH:57][cH:58]2)[cH:39][cH:40]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-be4638da590e4538b91f276e30e6508c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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