Dimethyl Sulfoxide → Des-4-methylenepiperidine Efinaconazole
Reaction equation
[CH3:28][S:29]([CH3:30])=[O:31].[F:8][c:9]1[c:10]([C:16]2([CH:19]([CH3:20])[OH:21])[O:17][CH2:18]2)[cH:11][c:12]([F:15])[cH:13][cH:14]1.[H-:6].[Na+:7].[OH:22][C:23]([C:24](=[O:25])[OH:26])=[O:27].[nH:1]1[n:2][cH:3][n:4][cH:5]1>>[n:1]1([CH2:18][C:16]([c:10]2[c:9]([F:8])[cH:14][cH:13][c:12]([F:15])[cH:11]2)([OH:17])[CH:19]([CH3:20])[OH:21])[n:2][cH:3][n:4][cH:5]1Participants
7
Sources & evidence
- ORD record
- ord-3bd2b8f8d0434fb783fbe9e4b3455ebf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…