1-(4-(Trifluoromethyl)phenyl)piperazine → (5-Bromo-2-morpholin-4-yl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[c:6]([C:7](=[O:8])[Cl:9])[cH:10]1.[F:17][C:18]([c:19]1[cH:20][cH:21][c:22]([N:25]2[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]2)[cH:23][cH:24]1)([F:31])[F:32]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([N:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[c:6]([C:7](=[O:8])[N:28]2[CH2:27][CH2:26][N:25]([c:22]3[cH:21][cH:20][c:19]([C:18]([F:17])([F:31])[F:32])[cH:24][cH:23]3)[CH2:30][CH2:29]2)[cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-eca2e39c53a64c24a3c3aa1908d4566d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…