6-(Dimethylamino)pyridine-3-boronic acid → 4'-pyrimidin-5-ylspiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

HRID 2340814Notes

Reaction equation

HRID 2340814 reaction equation
[Br:1][c:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:22])[C:10]21[CH2:11][O:12][c:13]2[c:14]1[cH:15][c:16]1[c:17]([cH:21]2)[O:18][CH2:19][O:20]1.[CH3:32][N:33]([CH3:34])[c:35]1[n:36][cH:37][c:38]([B:39]([OH:40])[OH:41])[cH:42][cH:43]1.[n:23]1[cH:24][n:25][cH:26][c:27]([B:29]([OH:30])[OH:31])[cH:28]1>>[c:2]1(-[c:27]2[cH:26][n:25][cH:24][n:23][cH:28]2)[c:3]2[c:4]([cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:22])[C:10]21[CH2:11][O:12][c:13]2[c:14]1[cH:15][c:16]1[c:17]([cH:21]2)[O:18][CH2:19][O:20]1

Participants

4

Reactant 3

HCID 27632716-(Dimethylamino)pyridine-3-boronic acidHCID 2795193(Pyrimidin-5-yl)boronic acidHCID 592633724'-bromospiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1H)-one

Product 1

HCID 592633274'-pyrimidin-5-ylspiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

Sources & evidence

ORD record
ord-709553aba856435eaa6198b5430d34e9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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