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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2340827Generated: October 26, 2026

Dimethylformamide → (2-Methyl-4-{3-[3-(3-piperidin-1-yl-prop-1-ynyl)-5-(4-trifluoromethyl-phenylethynyl)-phenyl]-prop-2-ynyloxy}-phenoxy)-acetic acid methyl ester

https://huagongshe.com/reaction/2340827

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant1-Ethynyl-4-(trifluoromethyl)benzeneHCID 4348295—
Reactant(4-{3-[3-Bromo-5-(3-piperidin-1-yl-prop-1-ynyl)-phenyl]-prop-2-ynyloxy}-2-methyl-phenoxy)-acetic acid methyl esterHCID 67157959—
ReactantHCID 178420554HCID 178420554—
Product(2-Methyl-4-{3-[3-(3-piperidin-1-yl-prop-1-ynyl)-5-(4-trifluoromethyl-phenylethynyl)-phenyl]-prop-2-ynyloxy}-phenoxy)-acetic acid methyl esterHCID 67158106—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-8b91ba2bcd0449e681d4861b2e501493
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)