2-[4-(2-hydroxyethyl)piperazin-1-yl]-N-[2,4-bis(methylthio)-6-methyl-3-pyridyl]acetamide → (4-[2-(benzoxazol-2-ylthio)ethyl]piperazin-1-yl]-N-[2,4-bis(2,2,2-trifluoroethoxy)-6-methyl-3-pyridyl]acetamide
Reaction equation
[OH:1][CH2:2][CH2:3][N:4]1[CH2:5][CH2:6][N:7]([CH2:8][C:9]([NH:10][c:11]2[c:12]([S:13][CH3:14])[n:15][c:16]([CH3:17])[cH:18][c:19]2[S:20][CH3:21])=[O:22])[CH2:23][CH2:24]1.[OH:25][CH2:26][CH2:27][N:28]1[CH2:29][CH2:30][N:31]([CH2:34][C:35](=[O:36])[NH:37][c:38]2[c:39]([O:51][CH2:52][C:53]([F:54])([F:55])[F:56])[n:40][c:41]([CH3:50])[cH:42][c:43]2[O:44][CH2:45][C:46]([F:47])([F:48])[F:49])[CH2:32][CH2:33]1.[SH:57][c:58]1[nH:59][c:60]2[cH:61][cH:62][cH:63][cH:64][c:65]2[n:66]1.[SH:67][c:68]1[o:69][c:70]2[c:71]([n:72]1)[cH:73][cH:74][cH:75][cH:76]2>>[CH2:26]([CH2:27][N:28]1[CH2:29][CH2:30][N:31]([CH2:34][C:35](=[O:36])[NH:37][c:38]2[c:39]([O:51][CH2:52][C:53]([F:54])([F:55])[F:56])[n:40][c:41]([CH3:50])[cH:42][c:43]2[O:44][CH2:45][C:46]([F:47])([F:48])[F:49])[CH2:32][CH2:33]1)[S:67][c:68]1[o:69][c:70]2[c:71]([n:72]1)[cH:73][cH:74][cH:75][cH:76]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-b870e215ecc8447bbd8872116e23c6b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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