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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 234100Generated: October 25, 2026

N-methyl-N-(trimethylsilyl)trifluoroacetamide → HCID 178504300, compound

https://huagongshe.com/reaction/234100

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-N-(trimethylsilyl)trifluoroacetamideHCID 32510—
ReactantCytosineHCID 178418229—
SolventDichloromethaneHCID 6344—
ProductHCID 178504300HCID 178504300—

Reaction Conditions

Temperature-30 °C

Reaction Steps

A bis-trimethylsilylcytosine solution was prepared by suspending 5.78 g of cytosine in 75 ml of dichloromethane and adding 20.57 ml of N-methyl-N-trimethylsilyltrifluoroacetamide and cooling the resulting solution to -30° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05594124
Source datasetuspto-grants-1997_01
ORD IDord-e9d3e2f5662544128c28f77c6580743e
Source noteuspto-grants-1997_01