Dichloromethane → 2-Bromomethyl-5-(2-ethylbenzoimidazol-1-yl)-7-morpholin-4-ylthiazolo[5,4-d]pyrimidine

HRID 2341714Notes

Reaction equation

HRID 2341714 reaction equation
[CH2:1]([CH3:2])[c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[c:11]3[c:12]([n:13]1)[s:14][c:15]([CH2:17][OH:18])[n:16]3)[cH:25][cH:26][cH:27][cH:28]2.[Cl:33][CH2:34][Cl:35].[P:29]([Br:30])([Br:31])[Br:32]>>[CH2:1]([CH3:2])[c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[c:11]3[c:12]([n:13]1)[s:14][c:15]([CH2:17][Br:30])[n:16]3)[cH:25][cH:26][cH:27][cH:28]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24614Phosphorus tribromideHCID 59605840[5-(2-Ethylbenzoimidazol-1-yl)-7-morpholin-4-ylthiazolo[5,4-d]pyrimidin-2-yl]methanol

Product 1

HCID 596061112-Bromomethyl-5-(2-ethylbenzoimidazol-1-yl)-7-morpholin-4-ylthiazolo[5,4-d]pyrimidine

Sources & evidence

ORD record
ord-791eaaf4ee2b435f8f883107f7ba8fdc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…