反应详情

温度

100 °C

A mixture of 25 mL water, 50 mL acetone and 15.1 g (77 mmol) (CF3)2CHCO2H was heated in a stainless steel tube for 16 hours at 100° C. The reaction product was discharged from the reaction vessel and collected in a cold trap (-78° C.). A liquid (9 mL) was collected and based on 19F and 1H NMR was found to contain 20% acetone, 75% CF3CH2CF3 and 5% CF3CH=CF2. The crude product was distilled through a low-temperature column and a mixture (9.4 g) containing 95% CF3CH2CF3 and 5% CF3CH=CF2 was isolated. The conversion of (CF3)2CHCO2H was 85%.

1. customcollected in a cold trap (-78° C.)
2. customA liquid (9 mL) was collected
3. distillationThe crude product was distilled through a low-temperature column
4. additiona mixture (9.4 g) containing 95% CF3CH2CF3
5. custom5% CF3CH=CF2 was isolated