Water → [7-(6-Methoxy-3-trifluoromethyl-pyridin-2-yl)-[1,8]naphthyridin-4-yl]-(5-trifluoromethyl-pyrimidin-2-yl)-amine
Reaction equation
[C:24](=[O:25])([O-:26])[O-:27].[Cl:1][c:2]1[c:3]2[cH:4][cH:5][c:6](-[c:12]3[n:13][c:14]([O:22][CH3:23])[cH:15][cH:16][c:17]3[C:18]([F:19])([F:20])[F:21])[n:7][c:8]2[n:9][cH:10][cH:11]1.[Cs+:28].[Cs+:29].[NH2:30][c:31]1[n:32][cH:33][c:34]([C:37]([F:38])([F:39])[F:40])[cH:35][n:36]1.[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1.[OH2:41]>>[c:2]1([NH:30][c:31]2[n:32][cH:33][c:34]([C:37]([F:38])([F:39])[F:40])[cH:35][n:36]2)[c:3]2[cH:4][cH:5][c:6](-[c:12]3[n:13][c:14]([O:22][CH3:23])[cH:15][cH:16][c:17]3[C:18]([F:19])([F:20])[F:21])[n:7][c:8]2[n:9][cH:10][cH:11]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-4eaaaa33c18141c59572321e039b850f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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