Boron tribromide → 5-[2-(2-Chloro-4-hydroxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1-methyl-1H-pyridin-2-one

HRID 2342221Notes

Reaction equation

HRID 2342221 reaction equation
[B:26]([Br:27])([Br:28])[Br:29].[Cl:1][c:2]1[c:3]([CH:10]([C:11]([C:12]([F:13])([F:14])[F:15])([OH:16])[c:17]2[cH:18][cH:19][c:20](=[O:24])[n:21]([CH3:23])[cH:22]2)[CH3:25])[cH:4][cH:5][c:6]([O:8][CH3:9])[cH:7]1>>[Cl:1][c:2]1[c:3]([CH:10]([C:11]([C:12]([F:13])([F:14])[F:15])([OH:16])[c:17]2[cH:18][cH:19][c:20](=[O:24])[n:21]([CH3:23])[cH:22]2)[CH3:25])[cH:4][cH:5][c:6]([OH:8])[cH:7]1

Participants

3

Reactant 2

HCID 25134Boron tribromideHCID 574213135-[2-(2-Chloro-4-methoxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1-methyl-1H-pyridin-2-one

Product 1

HCID 574213145-[2-(2-Chloro-4-hydroxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1-methyl-1H-pyridin-2-one

Sources & evidence

ORD record
ord-9788d155728546878eef354cba14ba4c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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