HCID 22915015, compound → HCID 54005812, compound

HRID 234228Notes

Reaction equation

HRID 234228 reaction equation
[OH:1][C:2]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([CH3:12])=[C:6]([C:13]2[O:17][N:16]=[C:15]([CH3:18])[N:14]=2)[C:3]=1[CH:4]=O.[SH:19][CH2:20][C@H:21]([NH:28][C:29](=[O:31])[CH3:30])[C:22]1[O:26][N:25]=[C:24]([CH3:27])[N:23]=1>>[OH:1][C:2]1[C:3]([CH2:4][S:19][CH2:20][C@H:21]([NH:28][C:29](=[O:31])[CH3:30])[C:22]2[O:26][N:25]=[C:24]([CH3:27])[N:23]=2)=[C:6]([C:13]2[O:17][N:16]=[C:15]([CH3:18])[N:14]=2)[C:7]([CH3:12])=[C:8]([O:10][CH3:11])[CH:9]=1

Participants

3

Reactant 2

HCID 22915015HCID 22915015, compoundHCID 53936852HCID 53936852, compound

Product 1

HCID 54005812HCID 54005812, compound

Procedure

2-Hydroxy-4-methoxy-5-methyl-6-(3-methyl-1,2,4-oxadiazol-5-yl)-benzaldehyde and (R)-N-[2-mercapto-1-(3-methyl-1,2,4-oxadiazol-5-yl)-ethyl]-acetamide were subjected in an analogous manner to the procedure described in Example 1(g) to yield (R)-N-[2-[6-hydroxy-4-methoxy-3-methyl-2-(3-methyl-1,2,4-oxadiazol-5-yl)benzylsulfanyl]-1-(3-methyl-1,2,4-oxadiazol-5-yl)-ethyl]-acetamide as an oil.

Sources & evidence

ORD record
ord-e4302ddbde38405bae5d01d2dd17b765
Source dataset
uspto-grants-1997_01
Patent number
US05594135

Reaction notes

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