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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2342309Generated: November 2, 2026

Trifluoroacetic acid → 6-chloro-4'-(3-chlorophenyl)-1'-[3-(1,1-dioxo-thiomorpholin-4-yl)-propyl]-2'-(5-fluoro-2-methylphenyl)-spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione

https://huagongshe.com/reaction/2342309

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantThiomorpholine 1,1-dioxideHCID 6484228—
Reactant(1-Methoxyethyl)(trimethyl)silaneHCID 22400412—
Reactant6-chloro-4'-(3-chlorophenyl)-1'-(3-chloropropyl)-6'-(5-fluoro-2-methylphenyl)spiro[1H-indole-3,5'-piperidine]-2,2'-dioneHCID 77580789—
Product6-chloro-4'-(3-chlorophenyl)-1'-[3-(1,1-dioxo-thiomorpholin-4-yl)-propyl]-2'-(5-fluoro-2-methylphenyl)-spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dioneHCID 74370459—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-3d56128435eb472282afd377b546269f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)