HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2342367Generated: November 4, 2026
Tetrahydrofuran → Tert-butyl 4-hydroxy-4-[5-(3-methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate
https://huagongshe.com/reaction/2342367
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Lithium ion | HCID 28486 | — |
| Reactant | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| Reactant | Diisopropylamide | HCID 5062348 | — |
| Reactant | N-[3-methyl-5-(1,3-thiazol-5-yl)phenyl]-4-(trifluoromethyl)pyrimidin-2-amine | HCID 58456403 | — |
| Product | Tert-butyl 4-hydroxy-4-[5-(3-methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate | HCID 58456305 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (10/10) |
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| ORD ID | ord-6ec042d9262148ab9b23a39ef0aa776f |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (10/10) |
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