Potassium Cation → N-(4-amino-6-chloro-9H-beta-carbolin-8-yl)-nicotinamide

HRID 2342424Notes

Reaction equation

HRID 2342424 reaction equation
[CH3:37][OH:38].[Cl:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([NH:24][C:25](=[O:26])[C:27]([F:28])([F:29])[F:30])[cH:7][n:8][cH:9][c:10]3[nH:11][c:12]2[c:13]([NH:15][C:16]([c:17]2[cH:18][n:19][cH:20][cH:21][cH:22]2)=[O:23])[cH:14]1.[K+:31].[K+:32].[O-:33][C:34]([O-:35])=[O:36]>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([NH2:24])[cH:7][n:8][cH:9][c:10]3[nH:11][c:12]2[c:13]([NH:15][C:16]([c:17]2[cH:18][n:19][cH:20][cH:21][cH:22]2)=[O:23])[cH:14]1

Participants

5

Reactant 4

HCID 813Potassium Cation2×HCID 887MethanolHCID 19660Carbonate IonHCID 86595097N-[6-chloro-4-(2,2,2-trifluoro-acetylamino)-9H-beta-carbolin-8-yl]-nicotinamide

Product 1

HCID 11151897N-(4-amino-6-chloro-9H-beta-carbolin-8-yl)-nicotinamide

Sources & evidence

ORD record
ord-54e930eef30549058452be4517e7fdc0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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