Sodium ion → 1-(2-(7-Methoxyquinolin-4-yloxy)ethyl)-5-(thiophen-2-yl)pyridin-2(1H)-one

HRID 2342615Notes

Reaction equation

HRID 2342615 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](=[O:23])[n:6]([CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][n:14][c:15]3[cH:16][c:17]([O:21][CH3:22])[cH:18][cH:19][c:20]23)[cH:7]1.[C:32](=[O:33])([O-:34])[O-:35].[CH3:38][O:39][CH2:40][CH2:41][O:42][CH3:43].[Na+:36].[Na+:37].[Pd+2:44].[s:24]1[c:25]([B:29]([OH:30])[OH:31])[cH:26][cH:27][cH:28]1>>[c:2]1(-[c:25]2[s:24][cH:28][cH:27][cH:26]2)[cH:3][cH:4][c:5](=[O:23])[n:6]([CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][n:14][c:15]3[cH:16][c:17]([O:21][CH3:22])[cH:18][cH:19][c:20]23)[cH:7]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 80711,2-DimethoxyethaneHCID 19660Carbonate IonHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 27339602-Thiopheneboronic acidHCID 248844955-Bromo-1-(2-(7-methoxyquinolin-4-yloxy)ethyl)pyridin-2(1H)-one

Product 1

HCID 250171031-(2-(7-Methoxyquinolin-4-yloxy)ethyl)-5-(thiophen-2-yl)pyridin-2(1H)-one

Sources & evidence

ORD record
ord-c2b6b15bc70a4ac9beba17eb996ebdd0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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