Dichloromethane → 3-benzyl-5-(3-fluoro-4-hydroxyphenyl)-2-(4-fluorophenylamino)pyrimidin-4(3H)-one
Reaction equation
[B:32]([Br:33])([Br:34])[Br:35].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([NH:24][c:25]2[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]2)[n:10][cH:11][c:12](-[c:15]2[cH:16][c:17]([F:23])[c:18]([O:21][CH3:22])[cH:19][cH:20]2)[c:13]1=[O:14].[Cl:36][CH2:37][Cl:38]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([NH:24][c:25]2[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]2)[n:10][cH:11][c:12](-[c:15]2[cH:16][c:17]([F:23])[c:18]([OH:21])[cH:19][cH:20]2)[c:13]1=[O:14]Participants
4
Sources & evidence
- ORD record
- ord-1e14c93d0f794964979556dadc4725d5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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