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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2342780Generated: November 3, 2026

Dichloromethane → N-(2-tert-butyl-4-cyano-1-(2-hydroxyethyl)-1H-indol-5-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamide

https://huagongshe.com/reaction/2342780

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl chlorideHCID 57516850—
Reactant5-amino-2-tert-butyl-1-(2-hydroxyethyl)-1H-indole-4-carbonitrileHCID 58183222—
ProductN-(2-tert-butyl-4-cyano-1-(2-hydroxyethyl)-1H-indol-5-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamideHCID 46199645—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-cbfcedabcad14739a5c7edf2863ec022
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)