1-(4-Amino-3-fluorophenyl)pyridin-2-one → 4-chloro-N-(2-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenylamino)-2-oxoethyl)-2H-tetrazol-5-yl)cyclopenta-1,3-dienecarboxamide

HRID 2342868Notes

Reaction equation

HRID 2342868 reaction equation
[CH3:1][O:2][C:3]([CH2:4][n:5]1[n:6][c:7]([NH:10][C:11](=[O:12])[c:13]2[s:14][c:15]([Cl:18])[cH:16][cH:17]2)[n:8][n:9]1)=[O:19].[NH2:20][c:21]1[c:22]([F:34])[cH:23][c:24](-[n:27]2[c:28](=[O:33])[cH:29][cH:30][cH:31][cH:32]2)[cH:25][cH:26]1>>[C:3]([CH2:4][n:5]1[n:6][c:7]([NH:10][C:11](=[O:12])[c:13]2[s:14][c:15]([Cl:18])[cH:16][cH:17]2)[n:8][n:9]1)(=[O:19])[NH:20][c:21]1[c:22]([F:34])[cH:23][c:24](-[n:27]2[c:28](=[O:33])[cH:29][cH:30][cH:31][cH:32]2)[cH:25][cH:26]1

Participants

3

Reactant 2

HCID 221815481-(4-Amino-3-fluorophenyl)pyridin-2-oneHCID 42643127{5-[(5-Chloro-thiophene-2-carbonyl)-amino]-tetrazol-2-yl}-acetic acid methyl ester

Product 1

HCID 426431774-chloro-N-(2-(2-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenylamino)-2-oxoethyl)-2H-tetrazol-5-yl)cyclopenta-1,3-dienecarboxamide

Sources & evidence

ORD record
ord-696e78da77a74a25a9249e6bec84ad15
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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