1,4-Benzodioxan-6-ylamine → N4-(4-ethoxyphenyl)-N2-(3,4-ethylenedioxyphenyl)-5-fluoro-2,4-pyrimidinediamine

HRID 2342887Notes

Reaction equation

HRID 2342887 reaction equation
[CH2:19]1[O:20][c:21]2[cH:22][c:23]([NH2:24])[cH:25][cH:26][c:27]2[O:28][CH2:29]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([F:18])[c:6]([NH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH2:16][CH3:17])[cH:13][cH:14]2)[n:7]1>>[c:2]1([NH:24][c:23]2[cH:22][c:21]3[c:27]([cH:26][cH:25]2)[O:28][CH2:29][CH2:19][O:20]3)[n:3][cH:4][c:5]([F:18])[c:6]([NH:8][c:9]2[cH:10][cH:11][c:12]([O:15][CH2:16][CH3:17])[cH:13][cH:14]2)[n:7]1

Participants

3

Reactant 2

HCID 891481,4-Benzodioxan-6-ylamineHCID 220606042-chloro-N4-(4-ethoxyphenyl)-5-fluoro-4-pyrimidineamine

Product 1

HCID 22060247N4-(4-ethoxyphenyl)-N2-(3,4-ethylenedioxyphenyl)-5-fluoro-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-791ddb53a94346fb9856ce126f1a1eac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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