HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzo(B)Thiophene → a-(2-Benzo[b]thienyl)-3,4-(methylenedioxy)benzyl alcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzo(B)Thiophene | HCID 7221 | — |
| Reactant | Piperonal | HCID 8438 | — |
| Reactant | HCID 178418306 | HCID 178418306 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | a-(2-Benzo[b]thienyl)-3,4-(methylenedioxy)benzyl alcohol | HCID 49964046 | — |
Reaction Steps
α-(2-Benzo[b]thienyl)-3,4-(methylenedioxy)benzyl alcohol was prepared by the method of Example 40A using benzo[b]thiophene (7.5 mmoles, 1.0 g), t-BuLi (1.7M, 9.7 mmoles, 5.7 ml), piperonal (8.9 mmoles, 1.0 g) and THF (20 ml). Flash chromatography (20% ethyl acetate/hexanes) provided 1.6 g (74%) of a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05594021 |
| Source dataset | uspto-grants-1997_01 |
| ORD ID | ord-82b034f3015a4580945ff93e8ebe982e |
| Source note | uspto-grants-1997_01 |