Methanesulfonyl chloride → 6-[4-(4-{3-[4-(Methylsulfonyl)piperazin-1-yl]propoxy}phenyl)piperidin-1-yl]-3-(trifluoromethyl)-7,8-dihydro[1,2,4]triazolo[4,3-b]pyridazine
Reaction equation
[CH3:36][S:37]([Cl:38])(=[O:39])=[O:40].[N:1]1([CH2:7][CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][c:14]([CH:17]3[CH2:18][CH2:19][N:20]([C:23]4=[N:28][n:27]5[c:26]([n:31][n:30][c:29]5[C:32]([F:33])([F:34])[F:35])[CH2:25][CH2:24]4)[CH2:21][CH2:22]3)[cH:15][cH:16]2)[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([CH2:7][CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][c:14]([CH:17]3[CH2:18][CH2:19][N:20]([C:23]4=[N:28][n:27]5[c:26]([n:31][n:30][c:29]5[C:32]([F:33])([F:34])[F:35])[CH2:25][CH2:24]4)[CH2:21][CH2:22]3)[cH:15][cH:16]2)[CH2:2][CH2:3][N:4]([S:37]([CH3:36])(=[O:39])=[O:40])[CH2:5][CH2:6]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-487473f3b8d74068af06ad18ac45baf9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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