Methanol → 5-[6-(3-methoxy-propyl)-pyridin-3-yl]-1H-pyrrolo[2,3-b]pyridine

HRID 2343501Notes

Reaction equation

HRID 2343501 reaction equation
[CH3:1][O:2][CH2:3][C:4]#[C:5][c:6]1[cH:7][cH:8][c:9](-[c:12]2[cH:13][c:14]3[c:15]([n:16][cH:17]2)[nH:18][cH:19][cH:20]3)[cH:10][n:11]1.[CH3:23][OH:24].[H:21][H:22].[OH-:25].[OH-:27].[Pd+2:26]>>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][c:6]1[cH:7][cH:8][c:9](-[c:12]2[cH:13][c:14]3[c:15]([n:16][cH:17]2)[nH:18][cH:19][cH:20]3)[cH:10][n:11]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 595695945-[6-(3-methoxy-prop-1-ynyl)-pyridin-3-yl]-1H-pyrrolo[2,3-b]pyridineHCID 178418361HCID 178418361, compound

Product 1

HCID 595695885-[6-(3-methoxy-propyl)-pyridin-3-yl]-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record
ord-9ce0c207ae884e3099dff535966a1c87
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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