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HRID234381

反应详情

EQUATION

反应方程式

HRID 234381 的结构方程式

REACTANTS

反应物

2
结构：CC(C)c1ccc(B(O)O)cc1
HCID2773480

4-Isopropylphenylboronic acid

C9H13BO2

结构：O=S(=O)(c1ccc(Br)s1)n1cccc1
HCID23445587

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)c1ccc(-c2ccc(S(=O)(=O)n3cccc3)s2)cc1
HCID22998466

未命名化合物

收率 84%

PROCEDURE

实验过程

N-[5-(4-isopropylphenyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 33C, from 4-isopropylphenyl boronic acid and N-(5-bromothiophene sulfonyl)-pyrrole. Purification by column chromatography using 10% ethyl acetate/hexanes gave the pure sulfonamide as an off white colored solid in 84% yield, m.p. 112°-114° C.

WORKUP

后处理

  1. customPurification by column chromatography