Acetonitrile → methyl 3-[4-[(2,4-difluorobenzyl)oxy]-5-iodo-6-oxopyrimidin-1(6H)-yl]-4-methylbenzoate
Reaction equation
[CH3:43][C:44]#[N:45].[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[n:7][cH:8][n:9](-[c:13]3[cH:14][c:15]([C:16](=[O:17])[O:18][CH3:19])[cH:20][cH:21][c:22]3[CH3:23])[c:10](=[O:12])[cH:11]2)[cH:24][cH:25][c:26]([F:28])[cH:27]1.[I:35][N:36]1[C:37](=[O:38])[CH2:39][CH2:40][C:41]1=[O:42].[OH:29][C:30]([CH:31]([Cl:32])[Cl:33])=[O:34]>>[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[n:7][cH:8][n:9](-[c:13]3[cH:14][c:15]([C:16](=[O:17])[O:18][CH3:19])[cH:20][cH:21][c:22]3[CH3:23])[c:10](=[O:12])[c:11]2[I:35])[cH:24][cH:25][c:26]([F:28])[cH:27]1Participants
5
Sources & evidence
- ORD record
- ord-f9710181cc8441aabeeafff860204990
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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