HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzo(B)Thiophene → 6314-41-6
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzo(B)Thiophene | HCID 7221 | — |
| Reactant | 4-Chlorobenzaldehyde | HCID 7726 | — |
| Reactant | HCID 178418306 | HCID 178418306 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 6314-41-6 | HCID 237072 | — |
Reaction Steps
α-(2-benzo[b]thienyl)-4-chlorobenzyl alcohol was prepared by the method of Example 40A with benzo[b]thiophene (7.5 mmoles, 1.0 g), t-BuLi (1.7 m, 9.7 mmoles, 5.7 ml), 4-chlorobenzaldehyde (9.7 mmoles, 1.4 g) and THF (20 ml). The crude material (2.45 g) was taken forward without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05594021 |
| Source dataset | uspto-grants-1997_01 |
| ORD ID | ord-53f5cd5ecaea4950935e092c88a2e71f |
| Source note | uspto-grants-1997_01 |