Acetone → N-methyl-N-[1-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]quinazolin-5-yl]oxypropan-2-yl]acetamide
Reaction equation
[C:40](=[O:41])([O-:42])[O-:43].[CH3:1][C:2](=[O:3])[O:4][C:5](=[O:6])[CH3:7].[CH3:46][C:47](=[O:48])[CH3:49].[CH3:8][NH:9][CH:10]([CH2:11][O:12][c:13]1[c:14]2[c:15]([NH:23][c:24]3[cH:25][c:26]([CH3:38])[c:27]([O:30][c:31]4[cH:32][n:33][c:34]([CH3:37])[cH:35][cH:36]4)[cH:28][cH:29]3)[n:16][cH:17][n:18][c:19]2[cH:20][cH:21][cH:22]1)[CH3:39].[K+:44].[K+:45]>>[CH3:1][C:2](=[O:3])[N:9]([CH3:8])[CH:10]([CH2:11][O:12][c:13]1[c:14]2[c:15]([NH:23][c:24]3[cH:25][c:26]([CH3:38])[c:27]([O:30][c:31]4[cH:32][n:33][c:34]([CH3:37])[cH:35][cH:36]4)[cH:28][cH:29]3)[n:16][cH:17][n:18][c:19]2[cH:20][cH:21][cH:22]1)[CH3:39]Participants
6
Sources & evidence
- ORD record
- ord-a05b23fdefac4ad6bc0e887f470e9ef2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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