5-(4-Chloro-phenyl)-3-iodo-7-methyl-pyrazolo[1,5-a]pyrimidine → 5-[5-(4-Chloro-phenyl)-7-methyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid amide

HRID 2344162Notes

Reaction equation

HRID 2344162 reaction equation
[C:19](#[CH:20])[c:21]1[cH:22][cH:23][c:24]([S:26](=[O:27])(=[O:28])[NH2:29])[s:25]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH3:14])[cH:13]2)[n:15][cH:16][c:17]3[I:18])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH3:14])[cH:13]2)[n:15][cH:16][c:17]3[C:20]#[C:19][c:21]2[cH:22][cH:23][c:24]([S:26](=[O:27])(=[O:28])[NH2:29])[s:25]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 670013225-(4-Chloro-phenyl)-3-iodo-7-methyl-pyrazolo[1,5-a]pyrimidineHCID 860437955-Ethynylthiophene-2-sulfonamide

Product 1

HCID 670008495-[5-(4-Chloro-phenyl)-7-methyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid amide

Sources & evidence

ORD record
ord-073f2bab6035436cb9ffaca45128bce7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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