Dichloromethane → 2-(Chloromethyl)-5-[4-(3-piperidin-1-ylpropoxy)phenyl]-1,3,4-oxadiazole

HRID 2344343Notes

Reaction equation

HRID 2344343 reaction equation
[Cl:28][CH2:29][Cl:30].[N:1]1([CH2:7][CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][c:14](-[c:17]3[n:18][n:19][c:20]([CH2:22][OH:23])[o:21]3)[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[S:24]([Cl:25])([Cl:26])=[O:27]>>[N:1]1([CH2:7][CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][c:14](-[c:17]3[n:18][n:19][c:20]([CH2:22][Cl:26])[o:21]3)[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 21108859[5-[4-(3-Piperidin-1-ylpropoxy)phenyl]-1,3,4-oxadiazol-2-yl]methanol

Product 1

HCID 211084972-(Chloromethyl)-5-[4-(3-piperidin-1-ylpropoxy)phenyl]-1,3,4-oxadiazole

Sources & evidence

ORD record
ord-1f6d37e6d72c432ca50e6becacc00381
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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