Water → 3-[4-(1-Ethyl-4,4,6-trimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-3-trifluoromethoxy-phenyl]-acrylic acid tert-butyl ester
Reaction equation
[Br:10][c:11]1[cH:12][c:13]([O:33][C:34]([F:35])([F:36])[F:37])[c:14](-[c:17]2[c:18]([CH3:32])[cH:19][c:20]3[c:25]([cH:26]2)[N:24]([CH2:27][CH3:28])[C:23](=[O:29])[CH2:22][C:21]3([CH3:30])[CH3:31])[cH:15][cH:16]1.[C:1]([CH:2]=[CH2:3])(=[O:4])[O:5][C:6]([CH3:7])([CH3:8])[CH3:9].[CH:38]1([N:39]([CH:40]2[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45]2)[CH3:46])[CH2:47][CH2:48][CH2:49][CH2:50][CH2:51]1.[O:53]1[CH2:54][CH2:55][O:56][CH2:57][CH2:58]1.[OH2:52]>>[C:1]([CH:2]=[CH:3][c:11]1[cH:12][c:13]([O:33][C:34]([F:35])([F:36])[F:37])[c:14](-[c:17]2[c:18]([CH3:32])[cH:19][c:20]3[c:25]([cH:26]2)[N:24]([CH2:27][CH3:28])[C:23](=[O:29])[CH2:22][C:21]3([CH3:30])[CH3:31])[cH:15][cH:16]1)(=[O:4])[O:5][C:6]([CH3:7])([CH3:8])[CH3:9]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-cf6c425e086a44059fa6e1e113533264
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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