Dimethyl Sulfoxide → 4-(4-Amino-2,5-difluorophenyl)pyridine-2-carboxamide
Reaction equation
[CH3:11][C:12]([CH3:13])([O-:14])[CH3:15].[CH3:29][S:30](=[O:31])[CH3:32].[Cl:17][c:18]1[cH:19][c:20]([C:24](=[O:25])[NH2:26])[n:21][cH:22][cH:23]1.[K+:16].[NH2:1][c:2]1[cH:3][c:4]([F:10])[c:5]([OH:9])[cH:6][c:7]1[F:8].[Na+:28].[OH-:27]>>[NH2:1][c:2]1[cH:3][c:4]([F:10])[c:5](-[c:18]2[cH:19][c:20]([C:24](=[O:25])[NH2:26])[n:21][cH:22][cH:23]2)[cH:6][c:7]1[F:8]Participants
8
Sources & evidence
- ORD record
- ord-f6ff848e57d9476eae1ec8fafe6eea1e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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